Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

A comparative longevity study of traditional buildings between rural and urban areas in Pearl River Delta, China

The rapid economic development and urbanization in Pearl River Delta of China, have changed the physical environment dramatically but also led to a crisis of the short life span of contemporary housing. When the green building concept cannot help provide the appropriate answer, many scholars turn to traditional buildings. Unlike in rural cases, traditional buildings in urban area obviously exhibit diversity and long-term usage. However, most of current studies focus on the preservation of historical features but do not analyze why and how such buildings can last a such long time. Historical cases in both two areas might have a certain number of common sustainable factors because they evolved from a similar prototype in history. For a better understanding of their common features and why they have different performances, theories closely related to the longevity and the “level” strategy will be introduced. These theories aimed to increase the life span of buildings and pay more attention to the interrelation between people and built environment in the temporal dimension. Within this framework, several historical cases from the urban area and a traditional village will be compared and studied by using the “level” division method, and abundant longevity evidence will be revealed and analyzed. As part of a complex and consistent research aimed at constructing an evaluation system, the results of this investigation will initially evaluate their long-lasting performances qualitatively under the two different contexts

Air Quality and Key Variables in High-Density Housing

The high-rise and high-density housing development in nearby industry relocations is a general urban sprawl phenomenon in fast-growing cities in Southern China. Aside from the low price, the improved air quality in the suburban area is always a reason for home buyers, but the consistent monitoring of air quality and knowledge about how to plan housing estates are lacking. This paper investigates the relationship between the housing morphology and the air quality in three housing estates in Shenzhen. This research utilizes on-site monitoring equipment to examine negative air ions (NAIs) and fine particulate matter (PM2.5) and the Computational Fluid Dynamics (CFD) simulation to examine the air flow. This study reveals the effect of the urban form on the concentration of NAIs and PM2.5 in spatial variation. A correlation study between the configuration variables of the urban form and the CFD air flow pattern helps to identify the key variables influencing the air quality. This study concludes that in housing estates with good air quality of surroundings, the building density has no remarkable effect. However, the footprint of buildings, the layout of podiums, the roughness length of the building, the distance between buildings, the open space aspect ratio and the mean building height may have a remarkable impact on the air flow and quality. These findings may encourage high-density housing development and provide planning guidance for the configuration of housing forms in Southern China and subtropical climate regions around the world

The efficacy of probiotics supplementation for the treatment of atopic dermatitis in adults: a systematic review and meta-analysis

Background There is a lack of certain evidence for the therapeutic efficacy of probiotics for adult atopic dermatitis (AD). Methods PubMed, EMBASE, and the Cochrane Database were searched for relevant studies, and randomized controlled trials of AD describing treatment with single/mixed probiotic therapy were included. Changes in outcomes were calculated by standard mean difference (SMD) and 95% confidence interval (CI). Relative efficacies of the probiotics were ranked by the surface under the cumulative ranking (SUCRA). Results Nine studies with a total of 402 participants, including 208 AD patients who received probiotic treatments and 194 controls, were considered during the current analysis. A reduction in disease severity for probiotic supplementation compared to controls in both the short term (SMD: 0.63; 95% CI: 0.02–1.25) and the long term (SMD: 1.57; 95% CI: 0.66–2.49). There was a significant improvement in long-term quality of life after probiotic supplementation compared with controls (SMD: 0.74; 95% CI: 0.39–1.09). A mixture of L. salivarius (LS01) and Bifidobacterium (BR03) was found the highest probability of the best supplementation. Conclusions Probiotic supplementation decreases clinical severity and improves the quality of life among adult AD patients. The mixture of LS01 and BR03 appeared optimal